It has been reported that hypoglycemia is achieved by these compounds' abilities to reverse or reduce insulin resistance, increase the hepatic glucose output, decrease the rate of digestion, and stimulate insulin output and inhibition of intestinal glucose absorption [28]. Hypoxis hemerocallidea corm is rich in phytosterols (β-sitosterol) and hypoxide (that is converted to rooperol in the gut). Here, INS is linked to Insulin resistance.