Even though CCR1 and CCR5 share the same chemokine ligands, studies with unilateral ureteral obstruction and renal ischemia-reperfusion injury models have shown that CCR1 but not CCR5 is essential for T cells, macrophages, and neutrophils infiltration in the tubulointerstitial region of the kidney [81–83]. Here, CCR1 is linked to Ureteral obstruction.