A large number of genomic regions are significantly bound by ERRα only on growth factor treatment in SKBr3 cells (Fig. 1b,c and Supplementary Fig. 1b,d), including the region within the TFF1 promoter originally described29 as an EGF-induced ERRα binding site in MCF-7 breast cancer cells (Supplementary Fig. 1b). Here, TFF1 is linked to breast cancer.