TEK and psoriasis: The KCTie2 doxycycline-repressible murine model of psoriasis with transgenic expression in keratinocytes of the angiopoietin receptor Tie2 was reported to develop systemic inflammation and aortic root vasculitis in one third of the mice at 12 months of age and these mice had shortened time to occlusive thrombus formation in a model of photochemical carotid artery thrombosis [16].