For the different breast cancer characteristics, the sensitivity of BSGI for detecting luminal A breast cancer was inferior at 68.63 % (95%CI 53.97–80.48 %) compared to luminal B (89.58 %, 95 % CI 76.56–96.10 %), HER-2(+) type (94.12 %, 95 % CI 69.24–99.69 %) and triple negative breast cancer (82.76 %, 95 % CI 63.51–93.47 %) (Fig. 4a). The gene discussed is ERBB2; the disease is breast carcinoma.