LDLR and fetal growth restriction: 2011). In humans, IUGR men had an increased ratio of LDL cholesterol to HDL cholesterol compared to IUGR women (The Hertfordshire Cohort Study, 2006). Conversely, when fed a normal‐fat diet, Ldlr knock‐out female mice had higher cholesterol compared to male Ldlr knock‐out mice (Hatch et al. 2012). In our previous study, female IUGR rats fed a HFD in adulthood had higher serum cholesterol levels than male IUGR rats fed the same diet (Zinkhan et al. 2014).