2013; Öberg 2015), glutamate receptors (Okayama et al. 2012; Ahn et al. 2014), and cholinergic receptors (Robles et al. 2014). Indeed, GRIN2A is increased in some lung adenocarcinomas (Okayama et al. 2012; Xin et al. 2013). Thus, while the present results demonstrate an important new pathway of AHR by dietary Cd, they also are consistent with the known lung carcinogenesis potential of Cd (Waalkes 2003). Here, GRIN2A is linked to lung adenocarcinoma.