A log-rank test showed that baseline cardiovascular diseases, higher GAP stage (≥II), higher serum LDH level (≥180 U/L), higher serum SP-D level (≥194.7 ng/mL), higher neutrophil (≥1.77 %) and eosinophil (≥3.21 %) percentages in BAL fluid samples, and treatment with an immunosuppressive agent after diagnosis were associated with poor AE-free probability (P = 0.042, 0.002, 0.048, 0.014, 0.048, 0.009, and 0.009, respectively) (Table 2). Here, SFTPD is linked to cardiovascular disorder.