Phosphatase and tensin homolog (PTEN) was reported as a tumor suppressor gene that negatively regulates oncogenic pathway of phosphatidylinositol‐3‐kinase (PI3K)/Akt 32, was also found mutated in various cancers and its expression has been associated with tumor progression in a dose‐dependent fashion 33. The gene discussed is AKT1; the disease is neoplasm.