TNF and spondyloarthropathy: Briot et al. have shown in a 2-year study of 106 patients with Spondyloarthropathies receiving anti-TNF therapy that a significant increase in weight of 2.2 kg occurred in 2 years (mostly due to a significant gain in FM) in parallel with an increase in BMD (+5.8 % at the lumbar spine and +2.26 % at the femur) [36].