Moreover, the described potential clinical tumor suppressive impact of abundant NDRG2 mRNA expression is impaired in hormone-receptor negative breast cancer: While in luminal A breast cancer patients, therewith ER-positive tumors, abundant NDRG2 expression significantly predicted both a favorable RFS and OS, patients with basal-like breast cancer showed worse prognosis upon increased NDRG2 mRNA expression. Here, NDRG2 is linked to breast carcinoma.