When FGF23 (i.e., the second and third FGF23 tertiles) was included as an additional covariate in model 5, the association between the lowest α-Klotho tertile and LVH among patents with CKD stage G3a (odds ratio 2.45, 95% CI 1.12–5.33, P = 0.024) and that between the lowest α-Klotho tertile and low LVEF among patents with CKD stage G3b (odds ratio 3.21, 95% CI 1.06–9.71, P = 0.039) retained statistical significance. Here, FGF23 is linked to chronic kidney disease.