KL and chronic kidney disease: On the other hand, among patients with CKD stage G3a or G3b in the current population, the correlation between FGF23 and α-Klotho was not significant; in addition, the association between α-Klotho and LVH among patients with CKD stage 3a and that between α-Klotho and low LVEF among patients with CKD stage 3b remained statistically significant after entering FGF23 as an additional covariate in multivariate logistic regression analyses.