CSF2 and posterior cortical atrophy: Because the small number of cells that can be obtained from surgically removed tumors limits autologous approach, GVAX for PCa is composed of two human prostate cell lines, LnCaP (androgen sensitive derived from a lymph node metastasis) and PC3 (androgen insensitive derived from bone metastasis) as antigens source, which are transfected with GM-CSF, and then irradiated for safety [107,108].