SIX2 and breast cancer: Furthermore, SIX2 was statistically associated with RFS (HR: 1.22, 95% CI: 1.02–1.45; P = 0.327 and I2 = 12.9%; Fig. 6E) and MFS (HR: 1.24, 95% CI: 1.00–1.53; P = 0.478 and I2 = 0.0%; Fig. 6F), but not correlated with OS (HR: 1.08, 95% CI: 0.86–1.36; P = 0.748 and I2 = 0.0%; Fig. 6D) of whole breast cancer population.