During acute peritonitis, PPARγ agonist treatment increased macrophage phagocytosis of ANs in EPOR-MKO mice (Fig. 5k); however, EPO did not enhance this process during acute peritonitis in PPARγ-MKO mice (Fig. 5k), demonstrating the important contribution of PPARγ to mediating EPO-promoted efferocytosis. This evidence concerns the gene EPOR and peritonitis.