Recently, the same group found that, like in patients with non-Hodgkin lymphoma and RA [43], NMO patients carrying the V158F allele of the fragment c gamma receptor 3A (FCGR3A-F) have increased likelihood of incomplete B cell depletion and fivefold increase chance of relapse following rituximab treatment. Here, FCGR3A is linked to rheumatoid arthritis.