CCN2 and non-small cell lung carcinoma: A substantial decrease in CTGF mRNA levels was detected in lung cancerous tissues, regardless of gender (males and females: p < 0.0000001), patients age (age ≤ 60 years: p < 0.000001; age > 60 years: p < 0.0000001) and histological type of NSCLC (ADC: p < 0.0000001; SCC: p < 0.000001; LCC: p = 0.0007; carcinoid: p = 0.005; Table 1).