PTEN and neoplasm: PTEN H-scores were significantly lower in all examined tumor areas when compared to the normal colon mucosa (DAKO normal vs. lymph node p = 0,109, vs. main mass p = 0.005, vs. for all others: border, invasive front and lymph node metastasis p < 0.001, respectively; CellSignaling normal vs. all tumor regions p < 0.001).