RAB11A and open-angle glaucoma: The stains for Rab 5 (Fig 5A and 5B), an early endosome tracker [33], for rab11 (Fig 5C and 5D), a tracker of recycling endosomes [34], and for rab 9 and the mannose-6-phosphate receptor Fig 5E–5H), markers for late endosome and Golgi, were mostly dispersed throughout the cell, whereas in POAG-TFs, all four stains showed a high concentration at a single peri-nuclear foci.