EIF3K and myeloid sarcoma: In an in vitro model of neurodegeneration, anti-M9 antibodies that bind the MS “M9” immunodominant epitope caused neurodegeneration (as shown by Fluoro-Jade C staining), apoptosis, and changes in gene expression related to hnRNP A1 function and the clinical phenotype of MS patients (i.e., spastic paraparesis and ataxia) [11, 17, 27].