To address this point, C6 glioma cells were incubated with biotinylated CPPs containing the SH3 domain binding motif and tyrosines phosphorylated by c-Src (from amino acid 245 to 283), the same sequence excluding the tyrosines (from amino acid 266 to 283) or a consensus SH3 domain binding motif (from amino acid 274 to 283) (Figure 5A). The gene discussed is SRC; the disease is central nervous system cancer.