Kaplan-Meier survival analysis and log-rank test indicated that colon cancer patients with LAPTM4B *1/1 genotype showed a shorter overall survival (OS) when compared with those with LAPTM4B *1/2 and LAPTM4B *2/2 genotypes (OS rate 33.8% vs. 43.7% and 72.7%, P = 0.0025) (Fig 2A). This evidence concerns the gene LAPTM4B and malignant colon neoplasm.