The univariate Cox’s model for OS of colorectal and esophageal cancer patients displayed that LAPTM4B genotype was one of the prognostic factors in total colon cancer patients (P = 0.006; HR: 0.565, 95% CI: 0.377–0.846), not in rectal and esophageal cancer patients (P = 0.692 and 0.958, respectively) (Table 2). Here, LAPTM4B is linked to malignant colon neoplasm.