Moreover, all the mice bearing cancer cells with downregulation of PP4R2 (A549shPP4R2-1-GL or A549shPP4R2-2-GL) had median survival time of 47 days post inoculation that was 16 days earlier than mice bearing A549GL, A549EV-GL and A549shCont-GL (Figure 7E). This evidence concerns the gene PPP4R2 and cancer.