PATZ1 and lung cancer: To investigate whether ectopic PATZ1 or PP4R2 is sufficient to suppress lung cancer colonization/metastasis in vivo, we generated A549GL, A549EV-GL, A549shCont-GL, A549pPATZ1-GL, A549pPP4R2-GL, A549shPP4R2-1-GL, A549shPP4R2-2-GL, A549pPATZ1/shPP4R2-1-GL, or A549pPATZ1/shPP4R2-2-GL cells, stably expressing not only green fluorescent protein and luciferase (GL) but also empty vector (EV), control shRNA (shCont), PATZ1 (pPATZ1), PP4R2 (pPP4R2), PP4R2 shRNA (shPP4R2-1 or shPP4R2-2), or PATZ1 cDNA and shPP4R2 (pPATZ1/shPP4R2-1 or pPATZ1/shPP4R2-2) as indicated (Figure 6A).