PATZ1-induced PP4R2 was positively associated not only with inactivation of phospho-IKK but also inhibition of migration/invasion of lung cancer cells regardless of whether the lung cancer cells express wild p53 (A549), p53 null (H1299) or p53 mutant (CL1-0 and CL1-5) (Figure 3 and Supplementary Figures S5-S8). The gene discussed is PPP4R2; the disease is lung cancer.