Stimulation of lung cancer cells with PGE2 or growth factors (EGF, HGF, IGF-1) results in transient increase of phospho-AktS473, phospho-IKKα/βS176/180 and phospho-NF-κB p65S536 in the early phase (within 1 h) [5]. This evidence concerns the gene NFKB1 and lung cancer.