PATZ1 and lung carcinoma: An increase of the association of PATZ1 protein with the PP4R2 gene at about +363 of transcription start site region was observed in PIP3-treated A549 and CL1-5 lung cancer cells (Supplementary Figure S4C), indicating that PIP3 induces PATZ1 that directly binds to the promoter region of PP4R2 gene and turns on PP4R2 transcription.