PATZ1 and cancer: Immunoblot analysis of the lung tissue lysates showed that mice bearing cancer cells overexpressing PATZ1 or PP4R2 (A549pPATZ1-GL or A549pPP4R2-GL) had the lowest levels of phospho-IKKα/βS176/180, phospho-NF-κB p65S536, COX-2, Snail and EMT (Figure 7C).