In all three contexts, introducing POC CD4 testing led to infections averted over a one year horizon compared to laboratory CD4 testing: 1.72% (95% confidence interval: 0.36—4.31%) infections averted in CC context, 2.65% (0.17—8.78%) in ECT context, 3.09% (0.11—11.47%) in UTT context. Here, CD4 is linked to infection.