IQGAP3 and Cirrhosis: AUC for IQGAP3 was 0.822 (95 % CI 0.700–0.943, Fig. 2c, P < 0.01); when differentiating from cirrhosis, its sensitivity and specificity were 85.2 and 71.6 %, respectively, when the cut-off value was selected at 43.5 pg/mL.