LAMP2 and infection: We observed a significant decrease in the number of mycobacterial phagosomes positive for LAMP-2 in bone marrow macrophages (BMM) from Sort1−/− mice compared to mycobacterial phagosomes in Sort1+/+ BMM (Mean = 450.5 ± 47.29 vs. 303.4 ± 31.83, respectively) after 2 h of infection (Figs 2A and S4A).