COASY and neoplasm: Analyses of up- and downregulated genes revealed a strong interferon signature, with many interferon-stimulated genes, encoding cytokines/chemokines (Ccl2, Cxcl11 and Cxcl10), regulatory proteins (STAT, Slfn), enzymes (Oas, Mx, Igtp), lymphocyte antigens, nucleotide binding proteins and major histocompatibility complex (MHC) molecules (S6 Table) expressed more strongly in the allograft than in the original tumor.