In univariate survival analysis, EGFR gene amplification was associated with shortened time to recurrence (TTR, median) (22 vs. 57 months, log-rank test, p = 0.026; Cox test, p = 0.028, HR: 1.73, 95 % CI: 1.06–2.83) and with shortened cancer-specific survival (CSS, median) (29 vs. 57 months, log-rank test, p = 0.033; Cox test, p = 0.035, HR: 1.67, 95 % CI: 1.04–2.69) (Fig. 3). This evidence concerns the gene EGFR and cancer.