BACE1 and Alzheimer disease: To investigate whether AD characteristic amyloid aggregates were formed in the Aβ1-42×2 and AβPP-BACE1 flies, Drosophila brain sections of elav-Gal4-derived flies were analysed using the amyloid-specific dye p-FTAA (Aslund et al., 2009) (Fig. 5).