In particular, according to HCC modulated genes, a specific activation of several factors was deduced, including E2F1, ERBB2, CCND1, RABL6, HGF, MYC, VEGF, IRF1, TNF, STAT1, JUN, TRAF2, AKT, WNT1 and CTNNB1. The gene discussed is MYC; the disease is hepatocellular carcinoma.