In particular, our analysis of HCC samples predicted activation of the following factors: E2F1, ERBB2, CCND1, RABL6, HGF, MYC, VEGF, IRF1, TNF, STAT1, JUN, TRAF2, AKT, WNT1, CTNNB1. The gene discussed is AKT1; the disease is hepatocellular carcinoma.