These studies have shown that the same cluster of LTL-associated alleles (OBFC1, ZNF208, TERC, TERT, RTEL1, ACTP2, and NAF1) is a risk indicator for melanoma [4], lung cancer [57], and coronary heart disease [7], such that when the joint effect of the alleles results in a comparatively long LTL, the risk for melanoma and lung cancer is increased, whereas the risk for coronary heart disease is diminished. This evidence concerns the gene TERC and coronary artery disorder.