MTHFR and metabolic syndrome: As shown in Table 2, the wild- type MTHFR-rs1801133 genotype (CC) had a frequency of 49%, whereas the CT and TT genotypes were found in 43.8% and 7.3% of the control group, respectively, while these frequencies in the MetS group were 40.4% (CC), 41.5% (CT), 18.1% (TT).