One particular characteristic of atherosclerosis is the increased expression of various inflammatory mediators such as vascular cell adhesion molecule-1 (VCAM-1) (Mackesy and Goalstone 2011) and matrix metallopeptidase-9 (MMP-9), which is critical for the development of arterial lesions by regulating smooth muscle cell migration and matrix degradation (Cho 2002), in arterial lesions. This evidence concerns the gene MMP9 and atherosclerosis.