In the present study, we found that P-p38 MAPK was expressed in both the cytoplasm and nucleus of breast cancer cells and positively correlated with PR expression in those with the luminal A/B subtype while positively correlated with HER2 expression in those with the HER2-positive subtype only in both correlation analysis and multivariate logistic regression analysis. The gene discussed is ERBB2; the disease is breast cancer.