Although it cannot be concluded from this study that recombinant FSH implication for the first cycle of OI in PCOS infertile women is superior to CC, considering the cumulative effects of gonadotropins, the authors believe that rFSH could be more efficacious than CC and yield in better results during 3-6 cycles of OI if more studies with larger study population be done. The gene discussed is BRD2; the disease is polycystic ovary syndrome.