Given that the defect in embryogenesis in naa10 emerged at the globular stage (Fig. 2A, B), we examined whether the development of the hypophysis was affected in naa10. Asymmetric division of the hypophysis occurred normally in wild-type plants (Fig. 2A), whereas it was irregular in naa10 plants; no functional QC progenitor was created in naa10 embryos (Fig. 2B). Here, NAA10 is linked to hypophysitis.