Of note, in contrast to TCL1 mice, we could not detect a general increase of CD161+ or CD56+ T cells in CLL patients compared to healthy volunteers (not shown) and the overrepresented T cells were not restricted to expression of a particular Vβ element but showed a diverse set of Vβ elements with a bias towards Vβ20 usage in DN T cells (Figure 3). The gene discussed is NCAM1; the disease is B-cell chronic lymphocytic leukemia.