High levels of EGFR (positive in > 10% of the total living cells) in the CD45−CD105− cells was detected in 6 of 6 RMPAhigh and 13 of 16 RMPAlow gliomas analyzed; and high PLXNB2 expression in the CD45−CD105− cells was detected in 5 of 6 RMPAhigh and 11 of 16 RMPAlow gliomas analyzed. This evidence concerns the gene EGFR and central nervous system cancer.