ERBB2 and neoplasm: Applied prognostic factors of gastric cancer are limited to the clinicopathological properties in the routine setting today, and classically include the WHO histopathological type, Lauren-Järvi classification, size of the tumor, grade, invasion through the gastric wall (pT), vascular invasion, lymph node involvement (pN), etiological background (EBV or Helicobacter pylori) and HER2 overexpression [2, 5–7].