IGF1R and non-small cell lung carcinoma: Hence the view is that targeting IGF-1R signaling in the clinical setting of NSCLC in combination with either other targeted agents and/or chemotherapy will only be of benefit for a subset of NSCLC patients and ongoing research is aimed to reveal biomarkers that can enable NSCLC patient selection as pointed out in several recent reviews in the field [14-18, 20, 32].