Of note, K3-SPG containing phagocytes were stained with a variety of macrophages and dendritic cell markers including CD11b, CD11c, CD169, F4/80, and MARCO, and none of these markers were dominantly co-stained with the K3-SPG containing phagocytes, suggesting that K3-SPG were taken up by a mixture of different types of tumor resident phagocytes. This evidence concerns the gene ITGAX and neoplasm.