APOE and atherosclerosis: Herein, in order to evaluate the effect of systemic immunity against the outer membrane proteins of Enterobacteriaceae on atherosclerosis progression and on the proinflammatory status associated with hyperlipidic diet (WD), we immunized C57BL/6 wild type and ApoE−/− mice fed with WD against the outer membrane protein K36 (ompK36) of Klebsiella pneumoniae.