While many studies have shown that HuR can be regulated via its phosphorylation sites, we provide the first evidence that differential HuR phosphorylation states may regulate mRNA translation of the bound autism-associated genes Foxp1 and Foxp2. Sole phospho-sites have been involved in either inhibiting or promoting HuR activity26, 34, 35, 36. The gene discussed is ELAVL1; the disease is autism.