mDCs potently induced productive (Fig 3A) and latent infection (Fig 3B) of resting CD4+ T-cells at all titres of R5-tropic HIVNL4.3(AD8).EGFP, demonstrating the high efficiency of this system to facilitate infection of resting CD4+ T-cells. This evidence concerns the gene CD4 and disease arising from reactivation of latent virus.