Another recent study integrated TCGA data and validated three genes (CYP4B1, CEPT1, and CHMP4A) in HGS-OvCa from patients likely to be cured by initial cytoreductive surgery and adjuvant chemotherapy; the precise role of these genes in ovarian cancer pathophysiology remains to be elucidated [109]. The gene discussed is CYP4B1; the disease is ovarian cancer.