Yet CF mice do secrete dramatically higher concentrations of inflammatory mediators upon bacterial challenge, including the chemokines keratinocyte chemoattractant (KC/CXCL1, the functional CXCL8 analog in mice) and the macrophage inflammatory protein 2 (mip-2/CCL3) that can be measured in the bronchoalveolar lavage (BAL) fluid [63, 64]. Here, CXCL8 is linked to cystic fibrosis.