NOS3 and cardiac arrest: Evidence for cross‐talk between H2S and NO includes improvement in survival after cardiac arrest and cardiopulmonary resuscitation by H2S in an endothelial nitric oxide synthase (eNOS)‐dependent manner.38 An additional mechanism by which H2S confers cardioprotection against I/R injury and pressure‐overload heart failure is through its ability to enhance eNOS activity and thereby increase myocardial NO bioavailability.39, 40