Drr1, together with Nfkbia, is one of 243 commonly altered genes identified using 1,270 post-mortem tissues from 13 patient cohorts for four neurodegenerative diseases including ALS, PD, and Huntington’s disease (HD) (Fig. 5H and Supplemental Fig. S5B)45. This evidence concerns the gene FAM107A and amyotrophic lateral sclerosis.