The SNP showing the smallest P-value in the 20q13.33/LAMA5 region, rs1760073, was completely correlated (r2 = 1) with the best functional candidate, rs1741634, which was located in an intron of LAMA5. The region containing rs1741634 exhibited open chromatin, bound the glucocorticoid receptor transcription factor, which has been implicated in cancer [73], and interestingly, was located in a region showing different enhancer marks in CRC cell lines vs. normal colon and rectal tissues (Figure C in S1 Text). This evidence concerns the gene NR3C1 and cancer.