Several types of cancer cells, including breast carcinoma, communicate with each other as well as their neighboring cells via number of signaling pathways, including NF-κB (7, 8), Hedgehog (9), phosphatidylinositol 3-kinase-Akt (PI3K-Akt) (7, 10), Notch-epidermal growth factor receptor (Notch-EGFR) (11), and short non-coding RNA export and import (12–14). The gene discussed is AKT1; the disease is breast carcinoma.